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has major subject area list
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Antineoplastic Agents; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Pyridazines
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has minor subject area list
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Catalytic Domain; Humans; Molecular Dynamics Simulation; Mutation, Missense; Philadelphia Chromosome; Protein Binding; Protein Kinase Inhibitors; Treatment Failure
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information resource reference
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BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia. Cancer Cell. 2014 Sep 08; 26(3):428-442.
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label
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BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia.
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